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There are essentially two amino acid pools we are concerned with here–the circulating pool and intracellular pool, . When the body is in a state of starvation (and other catabolic instances), amino acids are released from muscle tissue into circulation and utilized by other body tissues. On the contrary, when protein anabolism is necessary, amino acids can be actively transported from circulation into the intracellular space of muscle cells and incorporated into proteins (thus synthesizing new protein).
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