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Binding of glucocorticoid leads to translocation of the ligand-receptor complex from the cytosol to the nucleus. As indicated above, the receptors for the retinoids (vitamin A and its derivatives) are identified as RAR (for retinoic acid receptors) and exist in at least three subtypes, RARα, RARβ and RARγ. In addition, there is another family of nuclear receptors termed the retinoid X receptors (RXR) that represents a second class of retinoid-responsive transcription factors. The RXR have been shown to enhance the DNA-binding activity of RAR and the thyroid hormone receptors (TRα and TRβ), deca durabolin 300 efectos secundarios. The RXR represent a class of receptors that bind the retinoid 9- cis -retinoic acid.
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