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The mechanically sensitive isoform IGF-IEc, also called mechano-growth factor, induces myofiber hypertrophy and enhances physical capacity of skeletal muscle. It is noteworthy that no significant increase was observed in the protein levels for IGF-I and IGF-II in skeletal muscle, astralean vs clenbuterol. The weak correlations of muscle mRNA levels with protein expression for IGF-I and IGF-II could have several causes.
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